Cell Culture Growth Factors and Hormones
Genscript Corporation FGF-R2 Fc Chimera Mouse
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 is a receptor for fibroblast growth factor and it has important roles in embryonic development and tissue repair especially bone and blood vessels FGFR2 has two naturally occurring isoforms FGFR2IIIb and FGFR2IIIc created by splicing of the third immunoglobulin-like domain FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining Like the other members of the fibroblast growth factor receptor family these receptors signal by binding to their ligand and dimerisation (pairing of receptors) which causes the tyrosine kinase domains to initiate a cascade of intracellular signals On a molecular level these signals mediate cell division growth and differentiation
Medchemexpress LLC CD6 Human HEK293 100ug
The CD6 protein is a cell adhesion molecule that mediates cell-cell contacts and regulates T cell responses through interaction with ALCAM/CD166 It functions as a costimulatory molecule promoting T cell activation proliferation and contributing to the formation of immune synapses CD6 Protein Human (HEK293 Fc) is the recombinant human-derived CD6 protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC CD6 Rat HEK293 Hi 500ug
CD6 a protein lacks essential conserved residue(s) necessary for propagating feature annotation CD6 Protein Rat (HEK293 His) is the recombinant rat-derived CD6 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC CD6 Rat HEK293 Hi 100ug
CD6 a protein lacks essential conserved residue(s) necessary for propagating feature annotation CD6 Protein Rat (HEK293 His) is the recombinant rat-derived CD6 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC CD5 Rat HEK293 Hi 10ug
CD5 protein a pivotal T-cell receptor regulates T-cell proliferation through interactions with CD72/LYB-2 Its potential interaction with PTPN6/SHP-1 underscores its involvement in critical signaling pathways CD5 Protein Rat (HEK293 His) is the recombinant rat-derived CD5 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC HY-P7043A 10ug Medchemexpress, IL-5 (CHO-expressed), Human CAS: Purity:>98%
Medchemexpress, HY-112617A 100mg Thalidomide-O-amido-PEG2-C2-NH2 (TFA) CAS:1957235-75-4 Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Genscript Corporation GH, Mouse
Growth Hormone (GH), is a member of the somatotropin / prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
STEMCELL Technologies Human Recombinant TGF-beta 1, Size: 1000 µg
Add this high-quality human recombinant transforming growth factor beta 1 (TGF-β1) to your cell culture workflow. TGF-β1 binds to serine-threonine kinase type I and II receptors and regulates diverse cellular phenotypes through the SMAD2/3 signal transduction pathway. Use TGF-β1 in combination with basic fibroblast growth factor (bFGF) to support the maintenance of human pluripotent stem cell (hPSC) cultures (Amit et al. Biol Reprod, 2004). TGF-β1 has also been used to regulate exogenous cell signaling (Massagué Nat Rev Mol Cell Biol, 2000) and modulate immune cell homeostasis (Letterio & Roberts Annu Rev Immunol, 1998). Human recombinant TGF-ꞵ1 from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 0.5 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: Cartilage-inducing factor, Differentiation inhibiting factor, LAP, Latency-associated peptide, TGFB1, TGF-beta-1, Transforming growth factor β 1. Visit STEMCELL.com for more information.
Genscript Corporation PDGF R beta/CD140bBiotin Hi
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains The PDGF-AA PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities Where as PDGF R alpha binds all three PDGF isoforms with high affinity PDGF R beta binds PDGF-BB only with high-affinity PDGF R plays an essential role in blood vessel development by promoting proliferation migration and recruitment of pericytes and smooth muscle cells to endothelial cells Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites